About ToxD4C

Revolutionizing Molecular Toxicity

ToxD4C is a cutting-edge deep learning framework that transforms how we predict and understand molecular toxicity, making drug discovery safer and more efficient.

Our Mission

To advance computational toxicology through innovative AI technologies, providing researchers and industry professionals with powerful tools for accurate toxicity prediction, ultimately contributing to safer drug development and chemical assessment.

Key Features

Advanced Toxicity Prediction

State-of-the-art deep learning framework for predicting 31 different molecular toxicity endpoints with high accuracy and reliability.

Multi-Modal Architecture

Innovative integration of Graph Neural Networks, Transformer architecture, and geometric information processing for comprehensive molecular analysis.

Uncertainty Quantification

Built-in uncertainty estimation provides confidence intervals for each prediction, enabling informed decision-making in critical applications.

Hierarchical Learning

Four-level hierarchical representation learning from atoms to molecules, mimicking how chemists understand molecular structures.

High Performance

Optimized for both accuracy and efficiency, with classification AUC scores of 0.85-0.92 and regression R² scores of 0.75-0.88.

Wide Applications

Supports drug discovery, chemical safety assessment, regulatory compliance, and environmental risk evaluation.

Technology Stack

Core AI Technologies

  • • Graph Neural Networks (GNN)
  • • Transformer Architecture
  • • SE(3) Equivariant Networks
  • • Bayesian Deep Learning
  • • Multi-task Learning
  • • Contrastive Learning

Chemical Informatics

  • • RDKit Molecular Processing
  • • 3D Conformer Generation
  • • Molecular Fingerprints
  • • Chemical Descriptors
  • • SMILES Processing
  • • Molecular Visualization

Our Team

Research Team

AI & Computational Chemistry

Leading experts in machine learning, computational chemistry, and toxicology research.

Development Team

Software Engineering

Experienced developers specializing in AI frameworks, web technologies, and scientific computing.

Domain Experts

Toxicology & Drug Discovery

Industry professionals providing domain knowledge and validation for toxicity prediction models.

Impact & Applications

Drug Discovery

Accelerate pharmaceutical research by providing early toxicity screening, reducing the need for expensive animal testing and improving the success rate of drug candidates.

Chemical Safety

Support regulatory compliance and environmental protection by enabling rapid assessment of chemical toxicity for new substances and industrial applications.

Research Advancement

Contribute to the scientific understanding of molecular toxicity mechanisms through interpretable AI models and comprehensive toxicity endpoint coverage.

Global Health

Promote safer chemical development and usage worldwide, contributing to public health protection and environmental sustainability.

Join the Revolution

Be part of the future of computational toxicology. Explore our platform, contribute to research, or collaborate with our team to advance molecular safety assessment.